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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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PACTR |
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Last refreshed on:
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29 May 2023 |
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Main ID: |
PACTR202005599385499 |
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Date of registration:
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16/04/2020 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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Folic acid: A new suggested prevention and treatment of COVID-19 infection.
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Scientific title:
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The host Epigenetic methylation repair in COVID-19 using Folic acid: A new suggested prevention and treatment. |
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Date of first enrolment:
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20/04/2020 |
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Target sample size:
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60 |
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Recruitment status: |
Pending |
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URL:
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https://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=10971 |
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Study type:
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Interventional |
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Study design:
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Parallel: different groups receive different interventions at same time during study,Randomised,Stratified allocation where factors such as age, gender, center, or previous treatment are used in the stratification,Sealed opaque envelopes
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Phase:
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Phase-2
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Countries of recruitment
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Egypt
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Contacts
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Name:
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Nadia
Ouda |
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Address:
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Manial street
35855
Cairo
Egypt |
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Telephone:
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+201225550500 |
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Email:
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nadia.ouda@kasralainy.edu.eg |
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Affiliation:
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Head of Department of Bacteriology and Human immunology. |
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Name:
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Hala
Salah |
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Address:
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Manial street
35855
Cairo
Egypt |
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Telephone:
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+201001447705 |
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Email:
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hala.salah@kasralainy.edu.eg |
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Affiliation:
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Dean of the faculty of Medicine and Professor of paediatrics. |
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Key inclusion & exclusion criteria
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Inclusion criteria: 1. Health care works at risk while caring for COVID-19 carriers and cases.
2. Asymptomatic carriers with positive PCR.
3. Non-critical symptomatic COVID-!9 cases diagnosed by PCR.
Exclusion criteria: Critical ICU admitted critical symptomatic COVID-!9 cases diagnosed by PCR. COVID-!9 cases diagnosed by PCR
Age minimum:
19 Year(s)
Age maximum:
44 Year(s)
Gender:
Both
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Health Condition(s) or Problem(s) studied
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COVID-19
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COVID-19
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Intervention(s)
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Folic acid oral tablet.
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Already established protocols for prevevntion and treatment
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Primary Outcome(s)
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a.The conversion of health care workers at risk of COVID-19 from negative to positive as measured by PCR in the control and intervention groups.
b.The conversion from positive to negative in asymptomatic carriers and non-critical symptomatic COVID-19 patients in the control and intervention groups.
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Secondary Outcome(s)
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Rate and number of cases converted from PCR positive to PCR negative and the time needed for such conversion in the experimental as compared to the control group among the populations of Asymptomatic carriers and non-critical cases .and percentage lost from the health care providers due to their infection with COVID-19 virus.
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Source(s) of Monetary Support
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Ethics review
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Status: Not approved
Approval date:
Contact:
maher.fawzi@kasralainy.edu.eg
Faculty of Medicine. Cairo university
+201222166937
maher.fawzi@kasralainy.edu.eg
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