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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: ClinicalTrials.gov
Last refreshed on: 28 June 2021
Main ID:  NCT04929691
Date of registration: 08/06/2021
Prospective Registration: No
Primary sponsor: New York University
Public title: The CircumVent Project: A CPAP/O2 Helmet Solution for Non-Invasive Ventilation Among Patients With COVID-19 CircumVent
Scientific title: The CircumVent Project: A CPAP/O2 Helmet Solution for Non-Invasive Ventilation Using an Implementation Research Framework
Date of first enrolment: November 13, 2020
Target sample size: 370
Recruitment status: Recruiting
URL:  https://clinicaltrials.gov/show/NCT04929691
Study type:  Interventional
Study design:  Allocation: Non-Randomized. Intervention model: Parallel Assignment. Primary purpose: Supportive Care. Masking: None (Open Label).  
Phase:  N/A
Countries of recruitment
Nigeria
Contacts
Name:     Andre Fenton, PhD
Address: 
Telephone: +1-212-992-6573
Email: afenton@nyu.edu
Affiliation: 
Name:     Babatunde L Salako, MBBS, FRCP
Address: 
Telephone:
Email:
Affiliation:  Nigerian Institute for Medical Research, Lagos, Nigeria
Key inclusion & exclusion criteria

Inclusion Criteria:

- Adult patients admitted to a study site with respiratory distress and suspected or
confirmed COVID-19 infection

Exclusion Criteria:

- Patients who do not meet eligibility criteria



Age minimum: 18 Years
Age maximum: 80 Years
Gender: All
Health Condition(s) or Problem(s) studied
COVID-19 Respiratory Infection
SARS-CoV-2 Acute Respiratory Disease
Intervention(s)
Device: CPAP helmet
Other: Standard of care non-helmet based CPAP ventilation
Primary Outcome(s)
Disposition [Time Frame: 1-4 weeks while on admission]
Pulse Oximetry [Time Frame: 1-4 weeks while on admission]
Respiratory rate [Time Frame: 1-4 weeks while on admission]
Secondary Outcome(s)
Acceptability of CPAP/O2 helmet solution for non-invasive management of COVID-19 [Time Frame: 1-4 weeks while on admission]
Adaptability of the strategy for implementing CPAP/O2 helmet solution [Time Frame: 1-4 weeks while on admission]
Feasibility of using CPAP/O2 helmet solution [Time Frame: 1- 4 weeks while on admission]
Secondary ID(s)
CDC Foundation Award 1085.1
Source(s) of Monetary Support
Please refer to primary and secondary sponsors
Secondary Sponsor(s)
Aliko Dangote Foundation
CDC Foundation
Nigerian Institute of Medical Research
Ethics review
Results
Results available:
Date Posted:
Date Completed:
URL:
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