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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: ClinicalTrials.gov
Last refreshed on: 20 September 2021
Main ID:  NCT04927871
Date of registration: 15/02/2021
Prospective Registration: No
Primary sponsor: Foundation for Public Health and Epidemiological Research of Venezuela
Public title: Hybridized Three Steps Intervention to Prevent Diabetes in Venezuela HITS
Scientific title: Hybridized Three Steps (HITS) Intervention to Prevent Diabetes in Venezuela: HITS Diabetes With Prevention, An EVESCAM Lifestyle Intervention Study
Date of first enrolment: November 16, 2020
Target sample size: 156
Recruitment status: Recruiting
URL:  https://clinicaltrials.gov/show/NCT04927871
Study type:  Interventional
Study design:  Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Prevention. Masking: None (Open Label).  
Phase:  N/A
Countries of recruitment
Venezuela
Contacts
Name:     Maria M Infante, MD
Address: 
Telephone: +584125801131
Email: mariainfante384@gmail.com
Affiliation: 
Name:     Juan P Gonzalez-R, MD
Address: 
Telephone:
Email:
Affiliation:  Foundation for Public Health and Epidemiological Research of Venezuela
Key inclusion & exclusion criteria

Inclusion Criteria:

- Adults between 20 to 79 years years old

- No personal history of type 2 diabetes

- Body mass index = 25 kg/m2

- High risk for type 2 diabetes

Exclusion Criteria:

- Chronic ischemic heart disease: acute myocardial infarction, stable angina, unstable
angina.

- Stroke.

- Use of anticoagulants

- Severe renal failure

- Heart failure.

- Cannot do moderate-intensity physical activity

- Cannot attend most sessions

- Pregnancy or plans of having during the next sixth months

- Cancer or chemotherapy.

- Use of medications that affect weight (e.g. levothyroxine, pregabalin, orlistat)



Age minimum: 20 Years
Age maximum: 79 Years
Gender: All
Health Condition(s) or Problem(s) studied
Diabetes Mellitus, Type 2
Obesity
Overweight
PreDiabetes
Risk Factor, Cardiovascular
Intervention(s)
Behavioral: Diabetes Prevention Program
Behavioral: Diabetes Prevention Program 4 months
Behavioral: Medical Nutritional Therapy (MNT)
Behavioral: Total Diet Replacement (TDR)
Primary Outcome(s)
Change of weight in kilograms [Time Frame: 6 months]
Secondary Outcome(s)
Change in the points of Acceptance of the program assessed by a questionnaire using a Likert scale [Time Frame: 6 months]
Change in the points of Appropriateness of the core-curriculum assessed by a questionnaire using a Likert scale [Time Frame: 6 months]
Percentage of Attendance to the program [Time Frame: 6 months]
Percentage of Completion of the program. [Time Frame: 6 months]
Secondary ID(s)
FISPEVEN
Source(s) of Monetary Support
Please refer to primary and secondary sponsors
Secondary Sponsor(s)
Ethics review
Results
Results available:
Date Posted:
Date Completed:
URL:
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