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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: ClinicalTrials.gov
Last refreshed on: 20 September 2021
Main ID:  NCT04897269
Date of registration: 18/05/2021
Prospective Registration: Yes
Primary sponsor: Tu Du Hospital
Public title: Progesterone Supplementation on Women Having Low Progesterone Levels on Transfer Day
Scientific title: Effectiveness of Progesterone Supplementation for Women Having Low Progesterone Levels on the Day of Frozen Embryo Transfer
Date of first enrolment: May 20, 2021
Target sample size: 824
Recruitment status: Recruiting
URL:  https://clinicaltrials.gov/show/NCT04897269
Study type:  Interventional
Study design:  Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: Single (Outcomes Assessor).  
Phase:  Phase 3
Countries of recruitment
Vietnam
Contacts
Name:     Chau TM Le, PhD
Address: 
Telephone: 0084908429006
Email: dr.lethiminhchau@gmail.com
Affiliation: 
Name:     Chau TM Le, PhD
Address: 
Telephone: +84908429006
Email: dr.lethiminhchau@gmail.com
Affiliation: 
Name:     Chau TM Le
Address: 
Telephone:
Email:
Affiliation:  Department of Infertility, Tu Du Hospital
Key inclusion & exclusion criteria

Inclusion Criteria:

- Patients undergone ART with frozen embryo transfer, blastocyst or cleavaged stage
embryo transfer, from 18-45 years of age

- Normal BMI

- HRT for Endometrial preparation in FET cycles

Exclusion Criteria:

- Oocyte donor cycles

- Surrogacy

- IVM

- PGT

- Abnormal Uterine (firbroids 0 -> 3 according to FIGO classification, polyp,
adenomyosis, congenital malformation)

- Uterus fibroids type 4,5 (Figo classification) > 4cm

- History of recurrent implantation failure

- Endometrial thickness <7mm on the day of ET

- Cesarean scar defect (isthmocele)



Age minimum: 18 Years
Age maximum: 45 Years
Gender: Female
Health Condition(s) or Problem(s) studied
Assisted Reproductive Technology
Intervention(s)
Procedure: Progesterone supplementation
Primary Outcome(s)
Ongoing pregnancy rate [Time Frame: week 11 - 14 of pregnancy]
Secondary Outcome(s)
clinical pregnancy [Time Frame: 3 weeks after embryo transfer]
implantation rate [Time Frame: 3 weeks after embryo transfer]
Pregnancy rate [Time Frame: 2 weeks after embryo transfer]
Secondary ID(s)
656/BVTD-HDDD
Source(s) of Monetary Support
Please refer to primary and secondary sponsors
Secondary Sponsor(s)
Ethics review
Results
Results available:
Date Posted:
Date Completed:
URL:
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