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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ClinicalTrials.gov |
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Last refreshed on:
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23 January 2023 |
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Main ID: |
NCT02674958 |
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Date of registration:
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06/01/2016 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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Mobilization of Endothelial Progenitor Cells and Aspirin
TROPHIC 3 |
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Scientific title:
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Mobilization of Endothelial Progenitor Cells Following Alcohol Septal Ablation in Hypertrophic Obstructive Cardiomyopathy: Randomized Controlled Trial of Aspirin |
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Date of first enrolment:
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May 2016 |
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Target sample size:
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6 |
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Recruitment status: |
Terminated |
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URL:
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https://clinicaltrials.gov/show/NCT02674958 |
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Study type:
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Interventional |
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Study design:
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Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Basic Science. Masking: Single (Outcomes Assessor).
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Phase:
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Phase 3
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Countries of recruitment
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Canada
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Contacts
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Name:
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Aun-Yeong Chong, MD, MRCP |
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Address:
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Telephone:
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Email:
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Affiliation:
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OHIRC |
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Key inclusion & exclusion criteria
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Inclusion Criteria:
1. Patients who have been selected to undergo alcohol septal ablation for hypertrophic
obstructive cardiomyopathy based on clinical need
2. Age >18 years, <80 years
Exclusion Criteria:
1. Patients with known allergy to aspirin
2. Inability or refusal to consent to participate in the study
3. Patients who are on non-steroidal anti-inflammatory drugs and cannot be stopped for
the duration of the study
Age minimum:
18 Years
Age maximum:
80 Years
Gender:
All
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Health Condition(s) or Problem(s) studied
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Hypertrophic Obstructive Cardiomyopathy
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Intervention(s)
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Drug: Aspirin
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Primary Outcome(s)
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Maximum circulating endothelial progenitor cells as a ratio to baseline at any timepoint
[Time Frame: 0 hour, 1 hour, 6 hours, 24 hours, 72 hours and 7 days]
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Secondary Outcome(s)
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Endothelial cell migration in vitro compared to baseline at any timepoint
[Time Frame: 0 hour, 1 hour, 6 hours, 24 hours, 72 hours and 7 days]
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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