Secondary Outcome(s)
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Cartilage Damage at Week 36
[Time Frame: Week 36]
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Cartilage Damage at Week 52
[Time Frame: Week 52]
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Change From Baseline in Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 1
[Time Frame: From Baseline to Week 1]
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Change From Baseline in Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 24
[Time Frame: From Baseline to Week 24]
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Change From Baseline in the Cartilage Damage at Week 4
[Time Frame: From Baseline to Week 4]
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Change From Baseline in the Doppler Signal and Blood Flow at Week 24
[Time Frame: From Baseline to Week 24]
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Change From Baseline in the Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 1
[Time Frame: From Baseline to Week 1]
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Bone Erosion at Week 1
[Time Frame: Week 1]
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Bone Erosion at Week 2
[Time Frame: Week 2]
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Change From Baseline in the Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 12
[Time Frame: From Baseline to Week 12]
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Bone Erosion at Week 36
[Time Frame: Week 36]
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Bone Erosion at Week 6
[Time Frame: Week 6]
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Bone Erosion at Week 24
[Time Frame: Week 24]
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Cartilage Damage at Week 0
[Time Frame: Week 0 (Baseline)]
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Bone Erosion at Week 4
[Time Frame: Week 4]
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Cartilage Damage at Week 1
[Time Frame: Week 1]
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Change From Baseline in the Synovial Fluid and Proliferation at Week 24
[Time Frame: From Baseline to Week 24]
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Doppler Signal and Blood Flow at Week 0
[Time Frame: Week 0 (Baseline)]
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Bone Erosion at Week 8
[Time Frame: Week 8]
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Cartilage Damage at Week 12
[Time Frame: Week 12]
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Change From Baseline in the Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 6
[Time Frame: From Baseline to Week 6]
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Bone Erosion at Week 0
[Time Frame: Week 0 (Baseline)]
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Bone Erosion at Week 12
[Time Frame: Week 12]
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Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 6
[Time Frame: Week 6]
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Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 12
[Time Frame: Week 12]
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Change From Baseline in Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 12
[Time Frame: From Baseline to Week 12]
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Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 52
[Time Frame: Week 52]
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Synovial Fluid and Proliferation at Week 6
[Time Frame: Week 6]
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Change From Baseline in Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 2
[Time Frame: From Baseline to Week 2]
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Change From Baseline in Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 8
[Time Frame: From Baseline to Week 8]
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Bone Erosion at Week 52
[Time Frame: Week 52]
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Cartilage Damage at Week 2
[Time Frame: Week 2]
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Change From Baseline in the Bone Erosion at Week 12
[Time Frame: From Baseline to Week 12]
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Change From Baseline in the Bone Erosion at Week 6
[Time Frame: From Baseline to Week 6]
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Cartilage Damage at Week 24
[Time Frame: Week 24]
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Cartilage Damage at Week 8
[Time Frame: Week 8]
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Change From Baseline in the Cartilage Damage at Week 8
[Time Frame: From Baseline to Week 8]
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Change From Baseline in the Doppler Signal and Blood Flow at Week 2
[Time Frame: From Baseline to Week 2]
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Change From Baseline in the Doppler Signal and Blood Flow at Week 6
[Time Frame: From Baseline to Week 6]
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Change From Baseline in the Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 24
[Time Frame: From Baseline to Week 24]
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Change From Baseline in Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 6
[Time Frame: From Baseline to Week 6]
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Doppler Signal and Blood Flow at Week 1
[Time Frame: Week 1]
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Doppler Signal and Blood Flow at Week 8
[Time Frame: Week 8]
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Change From Baseline in the Cartilage Damage at Week 2
[Time Frame: From Baseline to Week 2]
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Change From Baseline in the Cartilage Damage at Week 36
[Time Frame: From Baseline to Week 36]
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Change From Baseline in the Bone Erosion at Week 36
[Time Frame: From Baseline to Week 36]
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Change From Baseline in the Bone Erosion at Week 52
[Time Frame: From Baseline to Week 52]
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Change From Baseline in the Doppler Signal and Blood Flow at Week 1
[Time Frame: From Baseline to Week 1]
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Change From Baseline in the Synovial Fluid and Proliferation at Week 4
[Time Frame: From Baseline to Week 4]
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Change From Baseline in the Cartilage Damage at Week 52
[Time Frame: From Baseline to Week 52]
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Change From Baseline in the Doppler Signal and Blood Flow at Week 36
[Time Frame: From Baseline to Week 36]
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Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 8
[Time Frame: Week 8]
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Synovial Fluid and Proliferation at Week 4
[Time Frame: Week 4]
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Doppler Signal and Blood Flow at Week 52
[Time Frame: Week 52]
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Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 12
[Time Frame: Week 12]
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Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 24
[Time Frame: Week 24]
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Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 36
[Time Frame: Week 36]
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Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 52
[Time Frame: Week 52]
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Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 1
[Time Frame: Week 1]
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Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 2
[Time Frame: Week 2]
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Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 24
[Time Frame: Week 24]
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Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 36
[Time Frame: Week 36]
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Synovial Fluid and Proliferation at Week 12
[Time Frame: Week 12]
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Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 4
[Time Frame: Week 4]
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Synovial Fluid and Proliferation at Week 36
[Time Frame: Week 36]
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Change From Baseline in the Synovial Fluid and Proliferation at Week 52
[Time Frame: From Baseline to Week 52]
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Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 2
[Time Frame: Week 2]
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Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 0
[Time Frame: Week 0 (Baseline)]
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Synovial Fluid and Proliferation at Week 0
[Time Frame: Week 0 (Baseline)]
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Synovial Fluid and Proliferation at Week 1
[Time Frame: Week 1]
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Synovial Fluid and Proliferation at Week 24
[Time Frame: Week 24]
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Cartilage Damage at Week 4
[Time Frame: Week 4]
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Cartilage Damage at Week 6
[Time Frame: Week 6]
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Change From Baseline in Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 4
[Time Frame: From Baseline to Week 4]
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Change From Baseline in Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 52
[Time Frame: From Baseline to Week 52]
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Change From Baseline in the Bone Erosion at Week 2
[Time Frame: From Baseline to Week 2]
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Change From Baseline in the Bone Erosion at Week 24
[Time Frame: From Baseline to Week 24]
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Change From Baseline in the Bone Erosion at Week 4
[Time Frame: From Baseline to Week 4]
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Change From Baseline in the Doppler Signal and Blood Flow at Week 52
[Time Frame: From Baseline to Week 52]
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Change From Baseline in the Doppler Signal and Blood Flow at Week 8
[Time Frame: From Baseline to Week 8]
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Change From Baseline in the Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 36
[Time Frame: From Baseline to Week 36]
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Change From Baseline in the Synovial Fluid and Proliferation at Week 6
[Time Frame: From Baseline to Week 6]
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Doppler Signal and Blood Flow at Week 2
[Time Frame: Week 2]
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Doppler Signal and Blood Flow at Week 24
[Time Frame: Week 24]
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Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 6
[Time Frame: Week 6]
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Change From Baseline in the Bone Erosion at Week 8
[Time Frame: From Baseline to Week 8]
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Change From Baseline in the Cartilage Damage at Week 1
[Time Frame: From Baseline to Week 1]
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Change From Baseline in the Cartilage Damage at Week 12
[Time Frame: From Baseline to Week 12]
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Change From Baseline in the Doppler Signal and Blood Flow at Week 12
[Time Frame: From Baseline to Week 12]
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Change From Baseline in the Synovial Fluid and Proliferation at Week 1
[Time Frame: From Baseline to Week 1]
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Change From Baseline in the Synovial Fluid and Proliferation at Week 2
[Time Frame: From Baseline to Week 2]
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Doppler Signal and Blood Flow at Week 12
[Time Frame: Week 12]
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Doppler Signal and Blood Flow at Week 4
[Time Frame: Week 4]
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Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 0
[Time Frame: Week 0 (Baseline)]
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Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 1
[Time Frame: Week 1]
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Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 8
[Time Frame: Week 8]
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Synovial Fluid and Proliferation at Week 2
[Time Frame: Week 2]
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Synovial Fluid and Proliferation at Week 52
[Time Frame: Week 52]
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Change From Baseline in Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 36
[Time Frame: From Baseline to Week 36]
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Change From Baseline in the Bone Erosion at Week 1
[Time Frame: From Baseline to Week 1]
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Change From Baseline in the Cartilage Damage at Week 24
[Time Frame: From Baseline to Week 24]
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Change From Baseline in the Cartilage Damage at Week 6
[Time Frame: From Baseline to Week 6]
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Change From Baseline in the Doppler Signal and Blood Flow at Week 4
[Time Frame: From Baseline to Week 4]
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Change From Baseline in the Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 2
[Time Frame: From Baseline to Week 2]
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Change From Baseline in the Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 4
[Time Frame: From Baseline to Week 4]
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Change From Baseline in the Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 52
[Time Frame: From Baseline to Week 52]
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Change From Baseline in the Sum of the Progression in the Doppler Signal, Cartilage Damage and Bone Erosion Score at Week 8
[Time Frame: From Baseline to Week 8]
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Change From Baseline in the Synovial Fluid and Proliferation at Week 12
[Time Frame: From Baseline to Week 12]
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Change From Baseline in the Synovial Fluid and Proliferation at Week 36
[Time Frame: From Baseline to Week 36]
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Change From Baseline in the Synovial Fluid and Proliferation at Week 8
[Time Frame: From Baseline to Week 8]
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Doppler Signal and Blood Flow at Week 36
[Time Frame: Week 36]
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Doppler Signal and Blood Flow at Week 6
[Time Frame: Week 6]
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Sum of the Synovial Fluid and Synovial Proliferation, and Doppler Signal/Blood Flow at Week 4
[Time Frame: Week 4]
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Synovial Fluid and Proliferation at Week 8
[Time Frame: Week 8]
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