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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
Register:
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ClinicalTrials.gov |
Last refreshed on:
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8 November 2021 |
Main ID: |
NCT00000945 |
Date of registration:
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02/11/1999 |
Prospective Registration:
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No |
Primary sponsor: |
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Public title:
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A Study to Evaluate the Use of Cidofovir (an Experimental Drug) for the Treatment of Progressive Multifocal Leukoencephalopathy (PML) in AIDS Patients
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Scientific title:
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A Pilot Study of the Effect of Cidofovir for the Treatment of Progressive Multifocal Leukoencephalopathy (PML) in Subjects With Acquired Immunodeficiency Syndrome (AIDS) |
Date of first enrolment:
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May 1999 |
Target sample size:
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24 |
Recruitment status: |
Completed |
URL:
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https://clinicaltrials.gov/show/NCT00000945 |
Study type:
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Interventional |
Study design:
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Primary purpose: Treatment.
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Phase:
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N/A
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Countries of recruitment
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United States
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Contacts
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Name:
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Marra CM |
Address:
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Telephone:
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Email:
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Affiliation:
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Name:
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Barker DE |
Address:
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Telephone:
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Email:
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Affiliation:
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Key inclusion & exclusion criteria
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Inclusion Criteria
You may be eligible for this study if you:
- Are HIV-positive.
- Have had symptoms of PML for no more than 90 days before study entry, or have had
abnormal neurological exams related to PML.
- Have negative tests for bacterial or fungal infections.
- Agree to practice abstinence or use effective methods of birth control during the
study.
- Are at least 18 years old.
- Have a life expectancy of at least 6 months.
Exclusion Criteria
You will not be eligible for this study if you:
- Have a history of uveitis.
- Are allergic to sulfa drugs or probenecid.
- Have had active opportunistic infections other than Kaposi's sarcoma within 30 days
before study entry.
- Have sickle cell anemia or trait.
- Are pregnant or breast-feeding.
Age minimum:
18 Years
Age maximum:
N/A
Gender:
All
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Health Condition(s) or Problem(s) studied
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HIV Infections
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Leukoencephalopathy, Progressive Multifocal
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Intervention(s)
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Drug: Cidofovir
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Drug: Probenecid
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Secondary ID(s)
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ACTG 363
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11327
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Source(s) of Monetary Support
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Please refer to primary and secondary sponsors
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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