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Main
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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register. |
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Register:
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ChiCTR |
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Last refreshed on:
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28 September 2020 |
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Main ID: |
ChiCTR2000037014 |
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Date of registration:
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2020-08-26 |
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Prospective Registration:
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Yes |
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Primary sponsor: |
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Public title:
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The predictive value of gut permeability in children with steroid dependent nephrotic syndrome
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Scientific title:
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The predictive value of gut permeability in children with steroid dependent nephrotic syndrome |
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Date of first enrolment:
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2020-10-01 |
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Target sample size:
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Steroid sensitive nephrotic syndrome group (SSNS group):40;Steroid dependent nephrotic syndrome group (SDNS group):30; |
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Recruitment status: |
Pending |
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URL:
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http://www.chictr.org.cn/showproj.aspx?proj=59710 |
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Study type:
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Observational study |
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Study design:
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Factorial
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Phase:
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0
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Countries of recruitment
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China
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Contacts
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Name:
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Kang Yulin
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Address:
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355 Luding Road, Putuo District, Shanghai, China
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Telephone:
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+86 18221992381 |
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Email:
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kangyulinmed@126.com |
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Affiliation:
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Department of Nephrology and Rheumatology, Shanghai Children's Hospital |
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Name:
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Kang Yulin
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Address:
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355 Luding Road, Putuo District, Shanghai, China
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Telephone:
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+86 18221992381 |
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Email:
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kangyulinmed@126.com |
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Affiliation:
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Department of Nephrology and Rheumatology, Shanghai Children's Hospital |
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Key inclusion & exclusion criteria
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Inclusion criteria: Children with onset primary nephrotic syndrome (PNS) are not treated before recruitment. Onset age 2-18 years old. The gender is not limited.
Exclusion criteria: (1) PNS patients with other organ diseases.
(2) Abnormal renal function (eGFR<90ml/min.1.73m^2).
Age minimum:
Age maximum:
Gender:
Both
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Health Condition(s) or Problem(s) studied
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Primary nephrotic syndrome
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Intervention(s)
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Steroid sensitive nephrotic syndrome group (SSNS group):Prednisone treatment recommended by the guidelines;Steroid dependent nephrotic syndrome group (SDNS group):Prednisone treatment recommended by the guidelines;
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Primary Outcome(s)
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Recurrence times;Ratio of urinary proteinuria and creatinine;Serum zonulin;Serum albumin;SEN, SPE, ACC, AUC of ROC;
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Source(s) of Monetary Support
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Shanghai Shenkang Hospital Development Center
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Ethics review
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Status: Approved
Approval date: 21/08/2020
Contact:
He Lei
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Results
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Results available:
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Date Posted:
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Date Completed:
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URL:
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